On the Poisons of Amanita Phalloides

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On the Poisons of Amanita Phalloides

It has recently been shown by one of us (W. W. Ford’) that the poisons of the fungus Amanita phalloides, the variety responsible for the great majority of deaths from mushroom intoxication, belong to the group of bacterial toxins. They were thus classified in virtue of their causing characteristic lesions in animals after a definite latent period, and because an immunity may be established towa...

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On the Poisons of Amanita Phalloides

It has recently been shown by one of us (W. W. Ford’) that the poisons of the fungus Amanita phalloides, the variety responsible for the great majority of deaths from mushroom intoxication, belong to the group of bacterial toxins. They were thus classified in virtue of their causing characteristic lesions in animals after a definite latent period, and because an immunity may be established towa...

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Antioxidant Properties of Amanita Phalloides Mushroom Toxins

Alpha amanitin and phalloidin are powerful hepatotoxins that belong to the main classes of toxins namely, amatoxins and phallotoxins, isolated from the deadly poisonous mushroom Amanita phalloides. It is well known that disruptions of antioxidant enzyme defense that include superoxide dismutase (SOD), catalase, glutathione peroxidase lead to generation of reactive oxygen species, followed by in...

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Diagnosis and Treatment of Amanita Phalloides-Type Mushroom Poisoning

The number of cases of mushroom poisoning is increasing as a result of the increasing popularity of "wild" mushroom consumption. Amanitin and phalloidin cytotoxins found in some Amanita and Galerina species produce the most severe and frequent life-threatening symptoms of Amanita phalloidestype poisoning. Delay in onset of symptoms, individual susceptibility variation and lack of rapid and reli...

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Mushroom poisoning is a relatively rare cause of acute liver failure (ALF). The present paper analyzes the pathogenesis, clinical features, prognostic indicators, and therapeutic strategies of ALF secondary to ingestion of Amanita phalloides, which represents the most common and deadly cause of mushroom poisoning. Liver damage from Amanita phalloides is related to the amanitins, powerful toxins...

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ژورنال

عنوان ژورنال: Journal of Biological Chemistry

سال: 1907

ISSN: 0021-9258

DOI: 10.1016/s0021-9258(17)46033-9